Search results for "Two sample"

REGGAE : a novel approach for the identification of key transcriptional regulators

2019

Abstract Motivation Transcriptional regulators play a major role in most biological processes. Alterations in their activities are associated with a variety of diseases and in particular with tumor development and progression. Hence, it is important to assess the effects of deregulated regulators on pathological processes. Results Here, we present REGulator-Gene Association Enrichment (REGGAE), a novel method for the identification of key transcriptional regulators that have a significant effect on the expression of a given set of genes, e.g. genes that are differentially expressed between two sample groups. REGGAE uses a Kolmogorov–Smirnov-like test statistic that implicitly combines assoc…

Environmentalism and Political Participation: Toward a New System of Social Beliefs and Values?

1992

This study examines the social beliefs and values of the Spanish population with regard to environmentalism. A questionnaire on environmental beliefs was produced and administered to two sample groups. The first group, to be called “activists” (comprising 86 subjects), is characterized by belonging to one or other environmental organization. The other, termed “nonactivists” (comprising 410 subjects), is composed of people not belonging to any environmentalist organization. We conclude that, as in other Western countries, environmentalism has moved from being a set of beliefs held by a small group of people to becoming a central element in the system of beliefs characterizing our society. In…

Catecholamine Response Curves of Male Hypertensives Identified by Lehmacher's Two Sample Configural Frequency Analysis

1997

A new application of LEHMACHER'S (1980) marginal homogeneity sign tests is given by analysis of bivariate response curves (or response surfaces) in two unpaired samples of hypertensive versus normotensive patients. Rationale and computations are illustrated by empirical data from sympathomedullary stress research.

Sequentially Rejective Test Procedures for Detecting Outlying Cells in One- and Two-Sample Multinomial Experiments

1985

For multiple testing of multinomial models in the case of one or two samples we propose using test procedures based on the principle described by MARCUS, PERITZ and GABRIEL (1976). These methods are based in each step of the sequentially rejective strategy on tests which exhaust the full α level (i.e. which are not conservative). The tests can be performed in a finite or asymptotic version.

Comparative study of two sample treatments for a liquid chromatography–tandem mass spectrometry determination of mycotoxin biomarkers in urine

2016

Differentiation among dairy products by combination of fast field cycling NMR relaxometry data and chemometrics

2021

A set of commercial milk and Sicilian cheeses was analysed by a combination of fast field cycling (FFC) nuclear magnetic resonance (NMR) relaxometry and chemometrics. The NMR dispersion (NMRD) curves were successfully analysed with a mathematical model applied on Parmigiano-Reggiano (PR) cheese. Regression parameters were led back to the molecular components of cheeses (water trapped in casein micelles, proteins and fats) and milk samples (water belonging to hydration shells around dispersed colloidal particles of different sizes and bulk water). The application of chemometric analysis on relaxometric data enabled differentiating milk from cheeses and revealing differences within the two sa…

Two‐sample problems in statistical data modelling

2010

A common problem in mathematical statistics is to check whether two samples differ from each other. From modelling point of view it is possible to make a statistical test for the equality of two means or alternatively two distribution functions. The second approach allows to represent the two‐sample test graphically. This can be done by adding simultaneous confidence bands to the probability‐probability (P — P) or quantile‐quantile (Q — Q) plots. In this paper we compare empirically the accuracy of the classical two‐sample t‐test, empirical likelihood method and several bootstrap methods. For a real data example both Q — Q and P — P plots with simultaneous confidence bands have been plotted…